**Introducing the First and Only hydrogel Dermal Regeneration Template**

Fesarius Therapeutics Announces FDA 510(k) clearance for Dermisphere hydrogel Dermal Regeneration Template

DUAL COLLAGEN DENSITIES

Facilitates rapid cell invasion and neovascularization

DermiSphere^TM hDRT is an advanced biphasic biomaterial that features a novel microarchitecture comprised of differential density interfaces created by combining a collagen based hydrogel with more dense collagen microspheres. DermiSphere^TM hDRT facilitated cell invasion
throughout the template 3 days after placement and becomes fully vascularized in just 7 days when vigorously tested pre-clinically.¹

DUAL RESORPTION TECHNOLOGY

Fosters an optimal healing environment to support tissue regeneration

Designed with different rates of resorption, the less dense hydrogel component is rapidly replaced by the patient’s own collagen, while the denser microspheres are replaced more slowly enabling the deposition of stable vascularized neodermal tissue.

The DermiSphereTM Difference

In a pre-clinical study, DermiSphere^TM hDRT facilitated fast and effective cellular invasion and vascularization of the template, leading to early, reliable deposition of functional neodermal tissue. By Day 3, DermiSphere^TM hDRT demonstrated 100% wound bed incorporation and fully vascularized the template by Day 7 (Figure 1).¹ Assessment of the newly formed dermal tissue revealed robust dermal thickness in DermiSphere^TM hDRT treated wounds of 1.5mm on day 7.¹

MAXIMIZED CONFORMABILITY

A pliable biomaterial that conforms to native tissue

The collagen hydrogel formula is designed to maximize
conformability, ensuring that DermiSphereTM hDRT
maintains intimate contact with the wound bed,
even in irregular wound topographies, ensuring
support of the wound healing process.

IMPROVED EASE OF USE

A translucent template that supports multidirectional cell invasion

DermiSphereTM hDRT is omnidirectional and can
be applied or adjusted in any direction without
compromising its fit or function. Additionally, it can
be trimmed in the wound bed, improving its ease of
use and simplifying the need to manage it clinically.

Choose the DermiSphere^TM Difference

Please call customer service
for more information:
1-833-900-HDRT
‍
customerservice@fesariustherapeutics.com

More DermiSphere hDRT

Introducing the First and Only hydrogel Dermal Regeneration Template